Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097062 | 0.88 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7210344 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5965074 | 0.81 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL7212067 | 0.81 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL1382367 | 0.81 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL5311097 | 0.81 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL7212040 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7210478 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5313386 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7215274 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059504-A1 | 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS | Rottapharm S.p.A. (IT) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008014821-A1 | 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS | ROTTAPHARM S.P.A. (IT) | 2008-02-07 | — | — | WO | disclosed |