Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 8/20 | 0.52 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094035 | 0.86 | PRKCZ (0.73) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL13926187 | 0.77 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL13838083 | 0.77 | PRKCZ (0.61) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL8188234 | 0.75 | KMT2A (0.65) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL15626984 | 0.75 | PRKCZ (0.53) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL3942905 | 0.75 | PRKCZ (0.68) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL2368512 | 0.74 | PRKCZ (0.68) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL6925391 | 0.74 | PRKCZ (0.51) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL2368735 | 0.73 | GRIN2C (0.56) | ALDH1A1MAPTHPGDGAARECQL | |
| SCHEMBL5918943 | 0.73 | PRKCZ (0.71) | ALDH1A1MAPTHPGDGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | ALDH1A1 1426/4885MAPT 3755/4885HPGD 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.