SCHEMBL4097320

SCHEMBL4097320

Cc1nc(-c2nc(C)c(C)n2C)c(C)c(C)c1C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL862543 0.74 IDO1 (0.31)
SCHEMBL862319 0.72 IDO1 (0.30)
SCHEMBL26326828 0.67
SCHEMBL12667569 0.65 IDO1 (0.31)
SCHEMBL16621762 0.65
SCHEMBL77010 0.64 IDO1 (0.35)
SCHEMBL17807589 0.64 MC4R (0.36) KDM4E
SCHEMBL16621758 0.64 DYRK1A (0.38)
SCHEMBL862412 0.62
Hydrochloric Acid SCHEMBL27173500 0.62 KDM4E (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094290-A1 Cationic Polymer Based Wired Enzyme Formulations for Use in Analyte Sensors ABBOTT DIABETES CARE INC. (US) 2018-04-05 US disclosed
US-9885073-B2 Cationic polymer based wired enzyme formulations for use in analyte sensors ABBOTT DIABETES CARE INC. (US) 2018-02-06 US disclosed
US-20170051329-A1 Cationic Polymer Based Wired Enzyme Formulations for Use in Analyte Sensors ABBOTT DIABETES CARE INC. 2017-02-23 US disclosed
US-20160296147-A1 Redox Polymers THERASENSE, INC. 2016-10-13 US disclosed
US-9428785-B2 Cationic polymer based wired enzyme formulations for use in analyte sensors ABBOTT DIABETES CARE INC. (US) 2016-08-30 US disclosed
US-9320467-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2016-04-26 US disclosed
US-20150090590-A1 Cationic Polymer Based Wired Enzyme Formulations for Use in Analyte Sensors ABBOTT DIABETES CARE INC. 2015-04-02 US disclosed
US-20140364710-A1 Redox Polymers THERASENSE, INC. 2014-12-11 US disclosed
US-8906211-B2 Cationic polymer based wired enzyme formulations for use in analyte sensors ABBOTT DIABETES CARE INC. (US) 2014-12-09 US disclosed
US-8828204-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2014-09-09 US disclosed
US-20130034664-A1 Biosensor Coating Composition and Methods Thereof ABBOTT DIABETES CARE INC. 2013-02-07 US disclosed
US-8226814-B2 Transition metal complexes with pyridyl-imidazole ligands ABBOTT DIABETES CARE INC. (US) 2012-07-24 US disclosed
US-20120138484-A1 Analyte Sensors Comprising Thickeners, Enzyme Stabilizers and Osmium Boronates ABBOTT DIABETES CARE INC. 2012-06-07 US disclosed
US-20120132525-A1 REDOX POLYMERS FOR USE IN ANALYTE MONITORING ABBOTT DIABETES CARE INC. 2012-05-31 US disclosed
US-8168052-B2 Transition metal complexes with bidentate ligand having an imidazole ring ABBOTT DIABETES CARE INC. (US) 2012-05-01 US disclosed
US-20110303537-A1 Redox Polymers ABBOTT DIABETES CARE INC. 2011-12-15 US disclosed
US-20110303538-A1 Redox Polymers ABBOTT DIABETES CARE INC. 2011-12-15 US disclosed
US-20110306111-A1 Redox Polymers ABBOTT DIABETES CARE INC. 2011-12-15 US disclosed
US-8070934-B2 For use as redox mediators in enzyme-based electrochemical sensors; electrolytic cells; glucose sensors for diabetes monitoring; kits ABBOTT DIABETES CARE INC. (US) 2011-12-06 US disclosed
US-7918976-B2 Transition metal complexes with bidentate ligand having an imidazole ring ABBOTT DIABETES CARE INC. (US) 2011-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170051329-A1 Cationic Polymer Based Wired Enzyme Formulations for Use in Analyte Sensors PEPD, MGAM, NAAA KDM4E 1719/4885
US-20180094290-A1 Cationic Polymer Based Wired Enzyme Formulations for Use in Analyte Sensors PEPD, MGAM, NAAA KDM4E 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.