SCHEMBL77010

SCHEMBL77010

Cc1nc(C)c(C)c(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9945369 0.83
SCHEMBL862543 0.81 IDO1 (0.31) IDO1
SCHEMBL12667569 0.78 IDO1 (0.31) IDO1
SCHEMBL862319 0.78 IDO1 (0.30) IDO1
SCHEMBL1251696 0.78 IDO1 (0.39) IDO1LMNA
SCHEMBL4639401 0.75 LMNA (0.48) IDO1LMNA
SCHEMBL2323940 0.75 LMNA (0.36) LMNA
SCHEMBL6069956 0.75
SCHEMBL439985 0.75 PDE10A (0.39)
SCHEMBL5053819 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110582869-A Battery separator and battery using the same 二氧化碳材料公司 2019-12-17 CN claimed
CN-107746565-A Thermoplastic polyurethane composite for slush molding and preparation method thereof 吉林大学 2018-03-02 CN claimed
US-7217814-B2 Methods of producing phosphitylated compounds HONEYWELL INTERNATIONAL INC. (US) 2007-05-15 US claimed
CN-1646452-A Process for preparing phosphitylated compounds HONEYWELL INT INC (US) 2005-07-27 CN claimed
US-20050124804-A1 Methods of producing phosphitylated compounds WERNER CHRISTIAN (DE) 2005-06-09 US claimed
EP-1476407-A2 METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS Honeywell International Inc. (US) 2004-11-17 EP claimed
US-20030232980-A1 Methods of producing phosphitylated compounds HONEYWELL INTERNATIONAL INC. 2003-12-18 US claimed
WO-2003072586-A2 METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS HONEYWELL INTERNATIONAL INC. (US) 2003-09-04 WO claimed
US-5162575-A Reacting organic base with halogenated amide in solvent OLIN CORPORATION (US) 1992-11-10 US claimed
WO-1992017442-A1 PROCESS FOR THE PREPARATION OF ISOCYANATES AND CARBAMATES USING A SILVER SALT PROMOTED HOFMANN REARRANGEMENT OLIN CORPORATION (US) 1992-10-15 WO claimed
US-5026917-A Acetylation of 2-methylnaphthalenes AMOCO CORPORATION (US) 1991-06-25 US claimed
EP-0220204-A1 THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1987-05-06 EP claimed
WO-1986006386-A1 THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1986-11-06 WO claimed
US-4575542-A Thermosettable polystyrylpyridine prepolymer terminated with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1986-03-11 US claimed
EP-0039205-B1 SELECTIVE PRODUCTION OF DIALKYLBENZENES MOBIL OIL CORPORATION (US) 1985-01-30 EP claimed
US-4359595-A ZEOLITE CATALYST CONVERSION OF ALCOHOL OR ETHER MOBIL OIL CORPORATION (US) 1982-11-16 US claimed
US-4300011-A FROM HYDROCARBONS USING ZEOLITE CATALYSTS AND HETEROCYCLE ORGANIC NITROGEN COMPOUNDS MOBIL OIL CORPORATION (US) 1981-11-10 US claimed
EP-0039205-A1 Selective production of dialkylbenzenes MOBIL OIL CORPORATION (US) 1981-11-04 EP claimed
US-4296243-A Process for producing sorbic acid or its derivatives DAICEL LTD. (JP) 1981-10-20 US claimed
US-4086229-A Dinitrosyldihalo complexes of molybdenum or tungsten PHILLIPS PETROLEUM COMPANY (US) 1978-04-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124804-A1 Methods of producing phosphitylated compounds PHOSPHO1, INPPL1, PLCB3 IDO1 3681/4885LMNA 2952/4885SMN1; SMN2 4783/4885
US-20030232980-A1 Methods of producing phosphitylated compounds PHOSPHO1, INPPL1, PLCG1 IDO1 2399/4885LMNA 2418/4885SMN1; SMN2 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.