Etiprednol Dicloacetate

Etiprednol Dicloacetate

SCHEMBL4097770

CCOC(=O)[C@@]1(OC(=O)C(Cl)Cl)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 12/20 0.78
▸ PGR P06401 7/20 0.78
▸ ABCB11 O95342 3/20 0.78
▸ NR1I2 O75469 2/20 0.78
▸ ABCC3 O15438 2/20 0.78
▸ HIF1A Q16665 5/20 0.67
▸ LMNA P02545 4/20 0.67
▸ CYP3A4 P08684 3/20 0.67
▸ USP2 O75604 1/20 0.67
▸ CYP2D6 P10635 1/20 0.67
▸ CYP2C9 P11712 1/20 0.67
▸ HSD17B10 Q99714 3/20 0.58
▸ NR3C2 P08235 3/20 0.58
▸ AR P10275 2/20 0.58
▸ TNF P01375 1/20 0.58
▸ IL6 P05231 1/20 0.58
▸ SERPINA6 P08185 1/20 0.58
▸ GLUL P15104 1/20 0.58
▸ ADAM17 P78536 1/20 0.58
▸ GPBAR1 Q8TDU6 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etiprednol Dicloacetate SCHEMBL13650061 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
Etiprednol Dicloacetate SCHEMBL20589422 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
Etiprednol Dicloacetate SCHEMBL13379814 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
Etiprednol Dicloacetate SCHEMBL1650565 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL8502600 0.94 NR3C1 (0.71) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7609828 0.93 NR3C1 (0.81) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL8505831 0.93 NR3C1 (0.70) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7614787 0.93 NR3C1 (0.72) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7612201 0.92 NR3C1 (0.68) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7611101 0.91 NR3C1 (0.68) NR3C1PGRABCB11NR1I2ABCC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034056-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING OCULAR DISEASES OR DISORDERS ALCON INC (CH) 2026-02-05 — — US claimed
US-20250312274-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2025-10-09 — — US claimed
US-20250302742-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2025-10-02 — — US claimed
EP-4531922-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER Chiesi Farmaceutici S.p.A. (IT) 2025-04-09 — — EP claimed
EP-4531920-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER Chiesi Farmaceutici S.p.A. (IT) 2025-04-09 — — EP claimed
EP-4531921-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER Chiesi Farmaceutici S.p.A. (IT) 2025-04-09 — — EP claimed
US-20250082588-A1 PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2025-03-13 — — US claimed
EP-4126138-B1 AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS INVOX BELGIUM NV (BE) 2024-10-16 — — EP claimed
WO-2024167694-A2 PLACENTAL EXTRACELLULAR MATRICES FOR OCULAR DELIVERY OF OPHTHALMIC THERAPEUTIC AGENTS CELULARITY INC. (US) 2024-08-15 — — WO claimed
WO-2023227783-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2023-11-30 — — WO claimed
WO-2023227781-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2023-11-30 — — WO claimed
WO-2023227782-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2023-11-30 — — WO claimed
US-20230347080-A1 PRESSURED METERED DOSE INHALERS COMPRISING A BUFFERED PHARMACEUTICAL FORMULATION CHIESI FARMACEUTICI S.P.A. (IT) 2023-11-02 — — US claimed
US-20230277451-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2023-09-07 — — US claimed
EP-4225267-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER Chiesi Farmaceutici S.p.A. (IT) 2023-08-16 — — EP claimed
US-20230080276-A1 PRESSURISED METERED DOSE INHALERS COMPRISING A BUFFERED PHARMACEUTICAL FORMULATION CHIESI FARMACEUTICI S.P.A. (IT) 2023-03-16 — — US claimed
EP-4106722-A1 PRESSURISED METERED DOSE INHALERS COMPRISING A BUFFERED PHARMACEUTICAL FORMULATION Chiesi Farmaceutici S.p.A. (IT) 2022-12-28 — — EP claimed
WO-2022074183-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2022-04-14 — — WO claimed
EP-0902789-B1 ANDROSTENE DERIVATIVES SOFT DRUGS INC (US) 2002-01-23 — — EP claimed
US-5981517-A FOR TREATING INFLAMMATIONS OF EYES, EARS, SKINS, INTESTINES, MOUTHS, ASTHMA, AND ARTHRITIS IN ANIMALS SOFT DRUGS, INC. (US) 1999-11-09 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034056-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING OCULAR DISEASES OR DISORDERS KDR, FLT4, FLT1 NR3C1 71/4885PGR 149/4885ABCB11 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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