Etiprednol Dicloacetate

Etiprednol Dicloacetate

SCHEMBL1650565

CCOC(=O)C1(OC(=O)C(Cl)Cl)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 12/20 0.78
▸ PGR P06401 7/20 0.78
▸ ABCB11 O95342 3/20 0.78
▸ NR1I2 O75469 2/20 0.78
▸ ABCC3 O15438 2/20 0.78
▸ HIF1A Q16665 5/20 0.67
▸ LMNA P02545 4/20 0.67
▸ CYP3A4 P08684 3/20 0.67
▸ USP2 O75604 1/20 0.67
▸ CYP2D6 P10635 1/20 0.67
▸ CYP2C9 P11712 1/20 0.67
▸ HSD17B10 Q99714 3/20 0.58
▸ NR3C2 P08235 3/20 0.58
▸ AR P10275 2/20 0.58
▸ TNF P01375 1/20 0.58
▸ IL6 P05231 1/20 0.58
▸ SERPINA6 P08185 1/20 0.58
▸ GLUL P15104 1/20 0.58
▸ ADAM17 P78536 1/20 0.58
▸ GPBAR1 Q8TDU6 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etiprednol Dicloacetate SCHEMBL4097770 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
Etiprednol Dicloacetate SCHEMBL13650061 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
Etiprednol Dicloacetate SCHEMBL20589422 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
Etiprednol Dicloacetate SCHEMBL13379814 1.00 NR3C1 (0.78) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL8502600 0.94 NR3C1 (0.71) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7609828 0.93 NR3C1 (0.81) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL8505831 0.93 NR3C1 (0.70) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7614787 0.93 NR3C1 (0.72) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7612201 0.92 NR3C1 (0.68) NR3C1PGRABCB11NR1I2ABCC3
SCHEMBL7611101 0.91 NR3C1 (0.68) NR3C1PGRABCB11NR1I2ABCC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230019058-A1 METHOD FOR THE TREATMENT OF VIRAL INFECTIONS SOFTHALE NV (BE) 2023-01-19 — — US disclosed
EP-4117670-A1 METHOD FOR THE TREATMENT OF A RESPIRATORY DISEASE, DISORDER, OR CONDITION RESULTING FROM A VIRAL INFECTION Softhale NV (BE) 2023-01-18 — — EP disclosed
CN-115315261-A Methods of treating respiratory diseases, disorders or conditions caused by viral infections 索芙特海尔公司 2022-11-08 — — CN disclosed
WO-2021180919-A1 METHOD FOR THE TREATMENT OF A RESPIRATORY DISEASE, DISORDER, OR CONDITION RESULTING FROM A VIRAL INFECTION SOFTHALE NV (BE) 2021-09-16 — — WO disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 — — US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019058-A1 METHOD FOR THE TREATMENT OF VIRAL INFECTIONS IL5, TSLP, CRH NR3C1 11/4885PGR 2218/4885ABCB11 3861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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