Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.37 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601995 | 0.87 | BRS3 (0.39) | DDB1CRBNHPGDSJAK2JAK1 | |
| SCHEMBL4116784 | 0.86 | CA1 (0.41) | DDB1CRBNHPGDSJAK2JAK1 | |
| SCHEMBL7602597 | 0.85 | CA1 (0.49) | DDB1CRBNHPGDSCDK1PFKFB3 | |
| Hydrochloric Acid SCHEMBL4097363 | 0.84 | CA1 (0.48) | DDB1CRBNHPGDSCDK1PFKFB3 | |
| SCHEMBL5131994 | 0.83 | BRS3 (0.39) | DDB1CRBNHPGDSJAK2JAK1 | |
| SCHEMBL3412817 | 0.82 | SMN1; SMN2 (0.42) | DDB1CRBNHPGDSCDK1PFKFB3 | |
| SCHEMBL4108477 | 0.82 | KDM4E (0.40) | DDB1CRBNJAK2JAK1TYK2 | |
| SCHEMBL3403165 | 0.82 | KMT2A (0.48) | HPGDSFADS1LMNAMAPT | |
| SCHEMBL3414984 | 0.81 | AURKA (0.41) | DDB1CRBNHPGDSJAK2JAK1 | |
| SCHEMBL4109902 | 0.81 | MAPT (0.44) | DDB1CRBNHPGDSJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227570-A1 | 2-AMINOQUINOLINES | HOFFMANN-LA ROCHE, INC. | 2009-09-10 | — | — | US | claimed |
| US-20090227570-A1 | 2-AMINOQUINOLINES | HOFFMANN-LA ROCHE, INC. | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227570-A1 | 2-AMINOQUINOLINES | HTR5A, HTR2C, HTR2A | DDB1 4738/4885CRBN 2795/4885HPGDS 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.