Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.86 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.84 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.84 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.84 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.84 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410629 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12295956 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL13873180 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL410688 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL410181 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL411122 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL15081846 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL14440563 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL14849220 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL13098028 | 1.00 | SLC6A4 (0.86) | SLC6A4KCNA5SCN5AKCND2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090483-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2013-04-11 | — | — | US | disclosed |
| US-8344162-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2013-01-01 | — | — | US | disclosed |
| US-20120271057-A9 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2012-10-25 | — | — | US | disclosed |
| US-20120065408-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2012-03-15 | — | — | US | disclosed |
| US-20070197632-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065408-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CYP2D6, CYP3A43, CYP2F1 | SLC6A4 919/4885KCNA5 56/4885SCN5A 39/4885 |
| US-20070197632-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | SLC6A4 1837/4885KCNA5 16/4885SCN5A 24/4885 |
| US-20130090483-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CYP2D6, CYP3A43, CYP2F1 | SLC6A4 919/4885KCNA5 56/4885SCN5A 39/4885 |
| US-20120271057-A9 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CYP2D6, CYP3A43, CYP2F1 | SLC6A4 919/4885KCNA5 56/4885SCN5A 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.