Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093339 | 0.90 | MAOA (0.39) | ALDH1A1MAPTACACBHSD17B10 | |
| SCHEMBL4095900 | 0.86 | EPHX2 (0.39) | ACACBKCNH2PTGS1PTGS2EPHX2 | |
| SCHEMBL4086721 | 0.83 | PTGES (0.48) | ACACBPTGS1PTGS2PTGESAPP | |
| SCHEMBL4105667 | 0.83 | PTGES (0.48) | ALDH1A1PTGESGFERHSD17B10 | |
| SCHEMBL4087011 | 0.81 | EPHX2 (0.38) | ACACBPTGS1PTGS2EPHX2APP | |
| SCHEMBL4096081 | 0.73 | MAOA (0.41) | ALDH1A1MAPTACACBHSD17B10 | |
| SCHEMBL4098949 | 0.70 | PTGES (0.41) | ALDH1A1MAPTPTGESGFERHSD17B10 | |
| SCHEMBL4097942 | 0.70 | PTGES (0.57) | ALDH1A1PTGES | |
| SCHEMBL4092023 | 0.68 | PTGES (0.48) | ALDH1A1MAPTPTGES | |
| SCHEMBL3578255 | 0.67 | PTGES (0.69) | ALDH1A1MAPTACACBHRH3PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | ALDH1A1 2718/4885MAPT 54/4885ACACB 4294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.