Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.64 |
| ▸ | PTAFR | P25105 | 9/20 | 0.56 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085974 | 0.91 | HSD17B1 (0.52) | HSD17B1PTAFRTLR7KMT2AMEN1 | |
| SCHEMBL4094282 | 0.91 | HSD17B1 (0.77) | HSD17B1PTAFRKMT2AMEN1USP2 | |
| SCHEMBL4094136 | 0.88 | HSD17B1 (0.82) | HSD17B1PTAFRTLR7KMT2AMEN1 | |
| SCHEMBL4102741 | 0.85 | HSD17B1 (0.65) | HSD17B1PTAFRTLR7MAPK1USP2 | |
| SCHEMBL4100708 | 0.83 | HSD17B1 (0.62) | HSD17B1MAPK1USP2ALDH1A1NPSR1 | |
| SCHEMBL4085481 | 0.82 | MAPT (0.47) | HSD17B1TLR7KMT2AMEN1ALDH1A1 | |
| SCHEMBL4093397 | 0.80 | TP53 (0.48) | HSD17B1KMT2AMEN1 | |
| SCHEMBL4101406 | 0.80 | HSD17B1 (0.61) | HSD17B1KMT2AMEN1MAPK1USP2 | |
| SCHEMBL4093157 | 0.79 | LMNA (0.61) | HSD17B1PTAFRKMT2AUSP2 | |
| SCHEMBL4093511 | 0.79 | HSD17B1 (0.67) | HSD17B1PTAFRTLR7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | HSD17B1 4/4885PTAFR 3930/4885TLR7 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.