SCHEMBL4099581

SCHEMBL4099581

CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OP(Cl)Oc1c(cc(C(C)(C)C)cc1C(C)(C)C)C2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33
GABBR2 O75899 1/20 0.33
GABBR1 Q9UBS5 1/20 0.33
CD69 Q07108 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9701123 0.90 GABBR2 (0.33) GABBR2GABBR1
SCHEMBL24882702 0.85 ELANE (0.34) ELANEGABBR2GABBR1CD69
SCHEMBL9131242 0.85 POLB (0.34) ELANECD69
SCHEMBL30712658 0.83 GABBR2 (0.36) ELANEGABBR2GABBR1CD69
SCHEMBL9298522 0.83 SMN1; SMN2 (0.37)
SCHEMBL4440720 0.83 GABBR2 (0.36) ELANEGABBR2GABBR1CD69
SCHEMBL9278611 0.83 ELANE (0.36) ELANEGABBR2GABBR1CD69
SCHEMBL29560929 0.83 ELANE (0.36) ELANEGABBR2GABBR1CD69
SCHEMBL9004174 0.82 ELANE (0.36) ELANEGABBR2GABBR1CD69
SCHEMBL7736384 0.82 GABBR2 (0.33) ELANEGABBR2GABBR1CD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5391799-A Process for the preparation 6-chloro-2,4,8,10-tetra-butyldibenzo[d,f][1,3,2]dioxaphoshepin CIBA-GEIGY CORPORATION (US) 1995-02-21 US claimed
JP-2289593-A None JP disclosed
EP-3334780-B1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2020-06-03 EP disclosed
US-10590263-B2 3-phenyl-benzofuran-2-one derivatives containing phosphorus as stabilizers BASF SE (DE) 2020-03-17 US disclosed
US-10259931-B2 3-phenyl-benzofuran-2-one derivatives containing phosphorus as stabilizers BASF SE (DE) 2019-04-16 US disclosed
EP-3428228-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2019-01-16 EP disclosed
EP-3428228-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2019-01-16 EP disclosed
US-20180237616-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2018-08-23 US disclosed
US-20180201760-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2018-07-19 US disclosed
US-20180201760-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2018-07-19 US disclosed
EP-0312790-B1 Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORP (US) 1993-11-18 EP disclosed
US-5136075-A Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1992-08-04 US disclosed
US-5061818-A Fluorination with metal or ammonium fluoride in presence of pyridine halide salt ETHYL CORPORATION (US) 1991-10-29 US disclosed
US-5049691-A Process for transhalogenating a halophosphorous compound with anhydrous hydrogen fluoride ETHYL CORPORATION (US) 1991-09-17 US disclosed
JP-H02289593-A N-HYDROCARBYLOXY HINDERED AMINE LIGHT STABILIZER SUBSTITUTED WITH PHOSPHORUS MOIETY CIBA GEIGY AG 1990-11-29 JP disclosed
EP-0389430-A1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
US-4929745-A Transhalogenation of halophosphorus compounds EHTYL CORPORATION (US) 1990-05-29 US disclosed
US-4910324-A Using a metal or ammonium fluoride ETHYL CORPORATION (US) 1990-03-20 US disclosed
EP-0357048-A2 Process for transhalogenating a halophosphorus compound with hydrogen fluoride ALBEMARLE CORPORATION (US) 1990-03-07 EP disclosed
EP-0353598-A2 Transhalogenation of halophosphorus compounds ETHYL CORPORATION (US) 1990-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10259931-B2 3-phenyl-benzofuran-2-one derivatives containing phosphorus as stabilizers IK, FIP1L1, PIR ELANE 4268/4885GABBR2 2183/4885GABBR1 2031/4885
US-20180201760-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS IK, FIP1L1, PIR ELANE 4268/4885GABBR2 2183/4885GABBR1 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.