Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 known ✓ | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 known ✓ | Q9UBS5 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24882702 | 0.83 | ELANE (0.34) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL30712658 | 0.82 | GABBR2 (0.36) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL4099581 | 0.82 | ELANE (0.33) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL29560929 | 0.82 | ELANE (0.36) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL9278611 | 0.82 | ELANE (0.36) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL4440720 | 0.82 | GABBR2 (0.36) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL9004174 | 0.81 | ELANE (0.36) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL5051101 | 0.79 | ELANE (0.35) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL10583884 | 0.78 | ELANE (0.34) | GABBR2GABBR1ELANECD69 | |
| SCHEMBL19648626 | 0.76 | ELANE (0.36) | GABBR2GABBR1ELANECD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198326-A1 | Polyolefin resin composition | AOYAMA TAIZO (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-0679684-B1 | POLYOLEFIN RESIN COMPOSITION | KANEGAFUCHI CHEMICAL IND (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0679684-A1 | POLYOLEFIN RESIN COMPOSITION | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-11-02 | — | — | EP | disclosed |