Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106868 | 0.85 | TSHR (0.67) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL4106959 | 0.82 | KMT2A (0.71) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1138712 | 0.82 | TSHR (0.74) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL12532631 | 0.79 | TSHR (0.47) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL7935169 | 0.78 | SLC6A2 (0.45) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1138561 | 0.76 | TSHR (0.44) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL4325797 | 0.76 | TSHR (0.38) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL4107541 | 0.75 | KMT2A (0.50) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL6754518 | 0.75 | SLC6A2 (0.45) | TSHRKMT2AGAASLC6A2SLC6A3 | |
| SCHEMBL562024 | 0.75 | SLC6A2 (0.45) | TSHRKMT2ACHRM2CHRM3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732168-B2 | Method of preparing ethylene polymers by controlled high pressure polymerization | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20130150542-A1 | Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization | BASF SE (DE) | 2013-06-13 | — | — | US | disclosed |
| US-8168725-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20110207892-A1 | DEGRADATION OF POLYPROPYLENE WITH HYDROXYLAMINE ESTER COMPOSITIONS | ROTH MICHAEL | 2011-08-25 | — | — | US | disclosed |