Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138561 | 0.86 | TSHR (0.44) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL13110328 | 0.83 | TSHR (0.56) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL13748133 | 0.82 | TSHR (0.36) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1138597 | 0.81 | TSHR (0.35) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL4325339 | 0.80 | TSHR (0.55) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL12862768 | 0.77 | KMT2A (0.43) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL4100145 | 0.76 | TSHR (0.49) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1139079 | 0.76 | SMN1; SMN2 (0.40) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1138712 | 0.74 | TSHR (0.74) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL14066748 | 0.72 | EPHX2 (0.36) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168725-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20110207892-A1 | DEGRADATION OF POLYPROPYLENE WITH HYDROXYLAMINE ESTER COMPOSITIONS | ROTH MICHAEL | 2011-08-25 | — | — | US | disclosed |
| US-7956109-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2011-06-07 | — | — | US | disclosed |
| US-20080234453-A1 | Method of Preparing Ethylene Polymers by Controlled High Pressure Polymerization | ROTH MICHAEL | 2008-09-25 | — | — | US | disclosed |
| US-20080045662-A1 | Degradation of Polypropylene with Hydroxylamine Ester Compositions | CIBA CORPORATION | 2008-02-21 | — | — | US | disclosed |