Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287083 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A3TSHRKMT2AHRH1 | |
| SCHEMBL562024 | 0.82 | SLC6A2 (0.45) | SLC6A2SLC6A3TSHRKMT2AHRH1 | |
| SCHEMBL6754518 | 0.82 | SLC6A2 (0.45) | SLC6A2SLC6A3TSHRKMT2AHRH1 | |
| SCHEMBL4106868 | 0.81 | TSHR (0.67) | SLC6A2SLC6A3TSHRKMT2AHRH1 | |
| SCHEMBL4106959 | 0.79 | KMT2A (0.71) | SLC6A2SLC6A3TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4100153 | 0.79 | TSHR (0.39) | SLC6A2SLC6A3TSHRKMT2AHRH1 | |
| SCHEMBL7935184 | 0.78 | SLC6A3 (0.41) | SLC6A2SLC6A3HRH1SLC6A4CARM1 | |
| SCHEMBL4100145 | 0.78 | TSHR (0.49) | SLC6A2SLC6A3TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7933489 | 0.77 | SLC6A2 (0.41) | SLC6A2SLC6A3HRH1SLC6A4CARM1 | |
| SCHEMBL17287078 | 0.75 | NAAA (0.49) | SLC6A2SLC6A3HRH1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265469-B1 | BLEND CONTAINING A STERIC HINDERED PIPERIDINYLOXY COMPOUND | DU PONT WIREX LTD (TW) | 2001-07-24 | — | — | US | disclosed |