SCHEMBL4100294

SCHEMBL4100294

CCOC(=O)C(C)(C)Oc1ccc(C(=O)CCc2cc(-c3ccc(C(F)(F)F)cc3)nn2C(C)C)cc1C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 18/20 0.40
PPARA Q07869 13/20 0.40
PPARG P37231 10/20 0.40
FBP1 P09467 1/20 0.36
GCGR P47871 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4100928 0.92 PPARD (0.39) PPARDPPARAPPARGFBP1
SCHEMBL1765886 0.91 PPARA (0.48) PPARDPPARAPPARG
SCHEMBL12648301 0.88 PPARD (0.38) PPARDPPARAPPARGGCGR
SCHEMBL30003505 0.88 PPARD (0.38) PPARDPPARAPPARGGCGR
SCHEMBL24742426 0.88 PPARD (0.38) PPARDPPARAPPARGGCGR
SCHEMBL4104227 0.87 PPARD (0.37) PPARDPPARAGCGR
SCHEMBL4102563 0.86 PPARD (0.38) PPARDPPARAPPARGFBP1GCGR
SCHEMBL4090763 0.85 PPARD (0.42) PPARDPPARAPPARG
SCHEMBL4095815 0.85 CRHR1 (0.40) PPARDPPARAPPARGFBP1
SCHEMBL4105589 0.85 PPARA (0.39) PPARDPPARAPPARGFBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta NIPPON CHEMIPHAR CO., LTD. (JP) 2009-09-24 US disclosed
EP-1854784-A1 ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR Nippon Chemiphar Co., Ltd. (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta PPARG, PPARA, PPARD PPARD 3/4885PPARA 2/4885PPARG 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.