SCHEMBL4100347

SCHEMBL4100347

OC(CCc1ccccc1)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.44
SLC1A3 P43003 2/20 0.43
SLC1A2 P43004 2/20 0.43
SLC1A1 P43005 2/20 0.43
CYP2D6 P10635 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
MMP12 P39900 1/20 0.43
TSHR P16473 1/20 0.43
HTR1A P08908 1/20 0.43
DRD2 P14416 1/20 0.43
DPP4 P27487 1/20 0.42
ANPEP P15144 2/20 0.42
ERAP1 Q9NZ08 2/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29172647 0.90 CA1 (0.48) CA1SLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL3779628 0.84 CA1 (0.44) CA1SLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL19511533 0.82 PPARG (0.49) CYP2D6MEN1KMT2ATSHRANPEP
SCHEMBL8760815 0.82 CA1 (0.43) CA1SLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL2076706 0.82 CA1 (0.43) CA1SLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL29087906 0.81 LTA4H (0.45) CA1SLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL4488619 0.81 LTA4H (0.45) CA1SLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL4536001 0.81 CA1 (0.50) CA1SLC1A3SLC1A2SLC1A1CYP2D6
SCHEMBL21924629 0.81 IDO1 (0.50) SLC6A3
SCHEMBL4285020 0.79 CA1 (0.41) CA1SLC1A3SLC1A2SLC1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10426131-B2 Fragrance composition GIVAUDAN S.A. (CH) 2019-10-01 US disclosed
US-10004205-B2 Fragrance composition GIVAUDAN SA (CH) 2018-06-26 US disclosed
US-20180070555-A1 Fragrance Composition GIVAUDAN S.A. (CH) 2018-03-15 US disclosed
EP-1865763-B1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2012-08-22 EP disclosed
US-20090126644-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2009-05-21 US disclosed
EP-1865763-A1 FRAGRANCE COMPOSITION Givaudan SA (CH) 2007-12-19 EP disclosed
WO-2006105680-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2006-10-12 WO disclosed