Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4121901 | 0.89 | ABL1 (0.52) | MAPTSMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL4106931 | 0.88 | MAPT (0.49) | MAPTSMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL4113425 | 0.88 | HTR3E (0.54) | MAPTSMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL4117739 | 0.87 | MAPT (0.49) | MAPTSMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL4101960 | 0.84 | ALDH1A1 (0.60) | MAPTSMN1; SMN2TP53ALDH1A1MMP2 | |
| SCHEMBL4113010 | 0.83 | EGFR (0.48) | MAPTSMN1; SMN2TP53EGFRHPSE | |
| SCHEMBL4105726 | 0.83 | GRIN1 (0.53) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL4113434 | 0.81 | CYP2D6 (0.52) | MAPTSMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL4107102 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL10967002 | 0.79 | ALDH1A1 (0.61) | MAPTSMN1; SMN2TP53THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263621-B2 | Tartrate derivatives for use as coagulation factor IXa inhibitors | SANOFI (FR) | 2012-09-11 | — | — | US | disclosed |
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | TFPI, TFPI2, F9 | MAPT 2888/4885SMN1; SMN2 4671/4885TP53 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.