Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095937 | 0.93 | FAAH (0.53) | FAAHMAPTPLA2G2AALOX5ALOX5AP | |
| SCHEMBL4098104 | 0.93 | FAAH (0.59) | FAAHMAPTPLA2G2ALMNA | |
| SCHEMBL2993129 | 0.91 | FAAH (0.51) | FAAHMAPTPLA2G2AALOX5ALOX5AP | |
| SCHEMBL4099761 | 0.91 | FAAH (0.58) | FAAHMAPT | |
| SCHEMBL4100773 | 0.91 | FAAH (0.45) | FAAHMAPTPLA2G2AALOX5APLMNA | |
| SCHEMBL3007091 | 0.90 | FAAH (0.48) | FAAHMAPTPLA2G2ALMNA | |
| SCHEMBL4089355 | 0.89 | FAAH (0.65) | FAAHMAPT | |
| SCHEMBL3010132 | 0.89 | FAAH (0.58) | FAAHMAPTLMNA | |
| SCHEMBL3002122 | 0.89 | FAAH (0.55) | FAAHMAPTLMNA | |
| SCHEMBL3005608 | 0.88 | FAAH (0.47) | FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610244-A1 | Indole compounds | Ironwood Pharmaceuticals, Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20090118503-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118503-A1 | FAAH INHIBITORS | FAAH, FAAH2, CNR2 | FAAH 1/4885MAPT 2737/4885PLA2G2A 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.