Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190459 | 0.93 | CYP4F2 (0.69) | CYP4F2CYP4A11THRBPKMAKR1B1 | |
| SCHEMBL759138 | 0.88 | CYP4F2 (0.56) | CYP4F2CYP4A11THRBPKMHTT | |
| SCHEMBL2116494 | 0.85 | CYP4F2 (0.62) | CYP4F2CYP4A11THRBPKMHTT | |
| SCHEMBL6254544 | 0.84 | CYP4F2 (0.85) | CYP4F2CYP4A11THRBPKMHTT | |
| SCHEMBL6257314 | 0.84 | CYP4F2 (0.85) | CYP4F2CYP4A11THRBPKMHTT | |
| SCHEMBL3280400 | 0.82 | CYP4F2 (0.56) | CYP4F2CYP4A11THRBPKMHTT | |
| SCHEMBL7941258 | 0.82 | CYP4F2 (0.69) | CYP4F2CYP4A11THRBPKMHTT | |
| SCHEMBL16280582 | 0.81 | CYP4F2 (0.50) | CYP4F2CYP4A11AKR1B1GPR84PPARG | |
| SCHEMBL186836 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11THRBPKMHTT | |
| SCHEMBL28100915 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11THRBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882684-B1 | PYRROLIDINE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-12-10 | — | — | EP | disclosed |
| US-7585886-B2 | Pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2009-09-08 | — | — | US | disclosed |
| US-20090062366-A1 | Pyrrolidine derivative or salt thereof | ASTELLAS PHARAMA INC. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1882684-A1 | PYRROLIDINE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-01-30 | — | — | EP | disclosed |
| EP-0765857-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | MITSUBISHI RAYON CO (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5773240-A | Optically active α-substituted carboxylic acid derivatives and method for producing the same | MITSUBISHI RAYON CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0765857-A1 | OPTICALLY ACTIVE ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI RAYON CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062366-A1 | Pyrrolidine derivative or salt thereof | CASR, CYP2R1, PTH1R | CYP4F2 473/4885CYP4A11 154/4885THRB 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.