SCHEMBL759138

SCHEMBL759138

CCOC(=O)C(C)(C)CCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.56
CYP4A11 Q02928 2/20 0.56
TSHR P16473 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 4/20 0.39
THRB P10828 2/20 0.39
CYP1A2 P05177 1/20 0.39
PKM P14618 3/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.38
HTT P42858 2/20 0.38
HPGD P15428 1/20 0.37
FFAR3 O14843 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
MMP8 P22894 2/20 0.37
PIN1 Q13526 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4100780 0.88 CYP4F2 (0.62) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL22190459 0.85 CYP4F2 (0.69) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL2021436 0.84 CYP4F2 (0.67) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL4577570 0.83 CYP4F2 (0.56) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL19875578 0.83 MMP8 (0.49) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL10816623 0.82 CYP4F2 (0.55) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL3283635 0.81 CYP4F2 (0.50) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL6762091 0.81 MEN1 (0.55) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL10815184 0.81 CYP4F2 (0.39) CYP4F2CYP4A11TSHRMEN1KMT2A
SCHEMBL5306680 0.80 CYP4F2 (0.62) CYP4F2CYP4A11TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034517-B1 Capacitors having conditioned carbon for electrodes Retriev Technologies Incorporated (US) 2015-05-19 US disclosed
WO-2015069854-A1 ELECTROLYTE SOLUTION FOR CAPACITORS AND BATTERIES Retriev Technologies Incorporated (US) 2015-05-14 WO disclosed
US-20150125760-A1 CAPACITORS HAVING CONDITIONED CARBON FOR ELECTRODES SOLSTICE ADVANCED MATERIALS US, INC. 2015-05-07 US disclosed
US-8785057-B1 Electrolyte solution for capacitors and batteries Retriev Technologies Incorporated (US) 2014-07-22 US disclosed
EP-2463282-B1 4-Benzylamino-1-carboxyacyl-piperidine derivatives as CETP inhibitors useful for the treatment of diseases such as hyperlipidemia or arteriosclerosis NOVARTIS AG (CH) 2013-08-07 EP disclosed
US-8440682-B2 4-benzylamino-1-carboxylacyl-piperidine derivatives as CETP inhibitors NOVARTIS AG (CH) 2013-05-14 US disclosed
US-8420641-B2 Method of inhibiting CETP activity with 4-benzylamino-1-carboxylacyl-piperidine derivatives NOVARTIS AG (CH) 2013-04-16 US disclosed
US-20120264773-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2012-10-18 US disclosed
US-20120208816-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2012-08-16 US disclosed
EP-2463282-A1 4-Benzylamino-1-carboxyacyl-piperidine derivatives as CETP inhibitors useful for the treatment of diseases such as hyperlipidemia or arteriosclerosis Novartis AG (CH) 2012-06-13 EP disclosed
US-20070002522-A1 Electric double layer capacitor and electrolytic solution therefor MITSUBISHI CHEMICAL CORPORATION (JP) 2007-01-04 US disclosed
US-5075488-A Fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-24 US disclosed
EP-0128006-B1 A SOIL-DISEASE-CONTROLLING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-18 EP disclosed
US-4709052-A FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-11-24 US disclosed
EP-0128006-A2 A soil-disease-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP disclosed
US-4479963-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1984-10-30 US disclosed
EP-0105919-A1 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. CIBA GEIGY AG (CH) 1984-04-25 EP disclosed
WO-1983003828-A1 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES CIBA-GEIGY AG (CH) 1983-11-10 WO disclosed
US-4401818-A HYPOTENSIVE AGENTS, CARDIOACTIVE AGENTS CIBA-GEIGY CORPORATION (US) 1983-08-30 US disclosed
US-4374847-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1983-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264773-A1 ORGANIC COMPOUNDS CETP, NPC1, CES1 CYP4F2 492/4885CYP4A11 105/4885TSHR 1637/4885
US-20120208816-A1 ORGANIC COMPOUNDS CETP, NPC1, CES1 CYP4F2 492/4885CYP4A11 105/4885TSHR 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.