Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792924 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL9861009 | 0.84 | SLC6A2 (0.48) | SLC6A2SLC6A3MEN1PRCPKMT2A | |
| SCHEMBL17982812 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A3MEN1PRCPKMT2A | |
| SCHEMBL2685822 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A3MEN1PRCPKMT2A | |
| Hydrochloric Acid SCHEMBL20721259 | 0.80 | SLC6A2 (0.55) | SLC6A2SLC6A3MEN1PRCPKMT2A | |
| SCHEMBL1401191 | 0.77 | OPRM1 (0.50) | SLC6A2SLC6A3MEN1PRCPKMT2A | |
| SCHEMBL13182999 | 0.77 | SLC6A2 (0.70) | SLC6A2SLC6A3MEN1PRCPKMT2A | |
| SCHEMBL2839265 | 0.74 | OPRM1 (0.63) | SLC6A2SLC6A3OPRM1OPRL1 | |
| SCHEMBL3786109 | 0.74 | SLC6A2 (0.38) | SLC6A2SLC6A3MEN1PRCPKMT2A | |
| SCHEMBL5460789 | 0.73 | OPRM1 (0.38) | SLC6A2SLC6A3MEN1PRCPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206156-B2 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20130116283-A1 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20090215828-A1 | Substituted indole derivatives | GRUNENTHAL GMBH (DE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215828-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | SLC6A2 198/4885SLC6A3 284/4885MEN1 3427/4885 |
| US-20130116283-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | SLC6A2 198/4885SLC6A3 284/4885MEN1 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.