SCHEMBL4101168

SCHEMBL4101168

OC(O)(c1ccccc1)c1cccc(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.47
HTR2A P28223 2/20 0.42
HTR2C P28335 2/20 0.42
OPRK1 P41145 2/20 0.42
KCNH2 Q12809 2/20 0.42
ADRA1A P35348 1/20 0.42
TSHR P16473 5/20 0.40
KCNA3 P22001 2/20 0.40
LMNA P02545 3/20 0.39
DRD2 P14416 3/20 0.39
DRD4 P21917 3/20 0.39
OPRM1 P35372 3/20 0.39
DRD3 P35462 3/20 0.39
CYP3A4 P08684 2/20 0.39
CYP19A1 P11511 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6369696 0.84 CYP3A4 (0.47) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL5742924 0.82 KCNN4 (0.46) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL7553448 0.82 KCNN4 (0.46) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL19130233 0.81 MEN1 (0.45) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL17295893 0.81 MEN1 (0.45) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL8055207 0.78 CYP2C9 (0.50) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL7782322 0.78 CYP2C19 (0.44) KCNN4TSHRCYP3A4CYP2C19HIF1A
SCHEMBL8601255 0.78 KCNN4 (0.48) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL699760 0.78 KCNN4 (0.59) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL31607641 0.78 KCNN4 (0.59) KCNN4HTR2AHTR2COPRK1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090023350-A1 Building construction felt paper with biocide/anti-microbial treatment ATLAS ROOFING CORPORATION (US) 2009-01-22 US disclosed
US-7410553-B2 Building construction felt paper with biocide/anti-microbial treatment ATLAS ROOFING CORPORATION (US) 2008-08-12 US disclosed
US-20060199454-A1 Building construction felt paper with biocide/anti-microbial treatment ATLAS ROOFING CORPORATION (US) 2006-09-07 US disclosed
EP-0135714-B1 SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS MELAMINE CHEMICALS, INC. (US) 1991-11-06 EP disclosed