SCHEMBL7782322

SCHEMBL7782322

OC(O)(c1ccccc1)c1ccccc1C(O)(O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.44
HIF1A Q16665 2/20 0.44
CYP1A2 P05177 4/20 0.42
CYP2C9 P11712 3/20 0.42
KCNN4 O15554 5/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
ALOX15 P16050 1/20 0.39
CYP2D6 P10635 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KCNE1 P15382 1/20 0.37
KCNQ1 P51787 1/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
CYP3A4 P08684 2/20 0.37
PTPN1 P18031 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8583178 0.85 ALDH1A1 (0.50) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL161069 0.84 CYP2C19 (0.50) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL8164004 0.81 CYP2C19 (0.48) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
Hydrochloric Acid SCHEMBL28294820 0.81 CYP2C19 (0.48) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL3830734 0.79 ALDH1A1 (0.44) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL538689 0.79 ALDH1A1 (0.52) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL9993667 0.78 KCNN4 (0.37) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL31140137 0.78 TRPA1 (0.45) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL4101168 0.78 KCNN4 (0.47) CYP2C19HIF1ACYP1A2CYP2C9KCNN4
SCHEMBL10670263 0.78 LMNA (0.46) CYP2C19HIF1ACYP2C9KCNN4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808822-B1 Method for preparing malonate group-containing acrylate monomers NIPPON PAINT CO LTD (JP) 2001-10-04 EP disclosed
US-6054606-A Method for preparing malonate group-containing acrylate monomers NIPPON PAINT CO., LTD. (JP) 2000-04-25 US disclosed
EP-0503958-B1 Heterocyclic compounds and their production NIPPON PAINT CO LTD (JP) 1998-09-23 EP disclosed
EP-0808822-A1 Method for preparing malonate group-containing acrylate monomers NIPPON PAINT CO., LTD. (JP) 1997-11-26 EP disclosed
US-5606096-A REACTING UNSATURATED CARBAMIC ACID DERIVATIVE WITH ALCOHOL RESIDUE IN THE ABSENCE OF A CATALYST NIPPON PAINT CO., LTD. (JP) 1997-02-25 US disclosed
EP-0556841-B1 Production of unsaturated carbamic acid derivative NIPPON PAINT CO LTD (JP) 1996-05-22 EP disclosed
US-5496943-A USING UNSATURATED ACYLISOCYANATE COMPOUNDS TO FORM OXAZOLINES, PYRANS WITH AMINOCARBONYLHETERO SUBSTITUTION AND GLUTARIMIDE DERIVATIVES AS CHEMICAL INTERMEDIATES NIPPON PAINT CO., LTD. (JP) 1996-03-05 US disclosed
EP-0478268-B1 Polymerizable substituted amide compound, polymer obtained therefrom and nonlinear optical material using the same NIPPON PAINT CO LTD (JP) 1995-11-15 EP disclosed
US-5442096-A Compound contains a alpha-ketoester and a polymerizable double bond NIPPON PAINT CO., LTD. (JP) 1995-08-15 US disclosed
US-5434296-A Reacting carbamate with metallic base to form salt; reacting with unsaturated acid halide to acylate NIPPON PAINT CO., LTD. (JP) 1995-07-18 US disclosed
EP-0294237-A2 Novel peroxide monomer and a polymer therefrom Nippon Paint Co., Ltd. (JP) 1988-12-07 EP disclosed
US-4788256-A PENDANT ISOCYANATOCARBONYL GROUP-CONTAINING ACRYLIC POLYMERS; COATINGS; ADHESIVES; MOLDING MATERIALS NIPPON PAINT CO., LTD. (JP) 1988-11-29 US disclosed
US-4769485-A Preparation of alkenoyl isocyanates NIPPON PAINT CO., LTD. (JP) 1988-09-06 US disclosed
EP-0232545-A2 Photocurable composition and cured article Nippon Paint Co., Ltd. (JP) 1987-08-19 EP disclosed
EP-0207621-A2 Functional polymers and their production Nippon Paint Co., Ltd. (JP) 1987-01-07 EP disclosed
EP-0206544-A2 Instantaneously curable composition Nippon Paint Co., Ltd. (JP) 1986-12-30 EP disclosed
EP-0204497-A1 Polymerisation process employing compounds having polymerisable acylurethane structures Nippon Paint Co., Ltd. (JP) 1986-12-10 EP disclosed
EP-0202840-A2 Isocyanate compounds and their production Nippon Paint Co., Ltd. (JP) 1986-11-26 EP disclosed
EP-0177122-A2 Acrylamide derivatives Nippon Paint Co., Ltd. (JP) 1986-04-09 EP disclosed
EP-0143613-A2 Production of isocyanate compounds NIPPON PAINT CO., LTD. (JP) 1985-06-05 EP disclosed