SCHEMBL4101344

SCHEMBL4101344

C=C(CCc1cc(-c2ccc(C(F)(F)F)cc2)nn1C(C)C)c1ccc(OC(C)(C)C(=O)O)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.47
PPARD Q03181 18/20 0.47
PPARG P37231 15/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765886 0.92 PPARA (0.48) PPARAPPARDPPARG
SCHEMBL4100928 0.91 PPARD (0.39) PPARAPPARDPPARG
SCHEMBL4105317 0.84 PPARD (0.46) PPARAPPARDPPARG
SCHEMBL4100294 0.83 PPARD (0.40) PPARAPPARDPPARG
SCHEMBL12732668 0.83 PPARA (0.44) PPARAPPARDPPARG
SCHEMBL24742426 0.82 PPARD (0.38) PPARAPPARDPPARG
SCHEMBL12648301 0.82 PPARD (0.38) PPARAPPARDPPARG
SCHEMBL30003505 0.82 PPARD (0.38) PPARAPPARDPPARG
SCHEMBL4100199 0.79 PPARD (0.45) PPARAPPARD
SCHEMBL4105650 0.79 PPARD (0.51) PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta NIPPON CHEMIPHAR CO., LTD. (JP) 2009-09-24 US disclosed
EP-1854784-A1 ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR Nippon Chemiphar Co., Ltd. (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta PPARG, PPARA, PPARD PPARA 2/4885PPARD 3/4885PPARG 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.