SCHEMBL4101907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6628829	0.97	HTR2C (0.54)	HTR2CPARP1MAPK10RIPK1MAPKAPK2
	SCHEMBL4525164	0.80	MAPKAPK2 (0.53)	HTR2CPARP1MAPK10RIPK1MAPKAPK2
	SCHEMBL28549389	0.78	SMN1; SMN2 (0.50)	PARP1ACHEEGFRALDH1A1KDM4E
	SCHEMBL28559488	0.78	SMN1; SMN2 (0.50)	PARP1ACHEEGFRALDH1A1KDM4E
	SCHEMBL13711871	0.78	KDM4E (0.57)	HTR2CMAPK10RIPK1KDM4EADRA1A
	SCHEMBL4114928	0.78	HTR2C (0.48)	HTR2CPARP1MAPK10RIPK1MAPKAPK2
	SCHEMBL24408232	0.77	NR2E1 (0.56)	HTR2CMAPK10RIPK1MAPKAPK2ADRA1A
	SCHEMBL31336631	0.77	ALDH1A1 (0.47)	PARP1EGFRALDH1A1KDM4ESMN1; SMN2
	SCHEMBL11838861	0.77	ALDH1A1 (0.47)	PARP1EGFRALDH1A1KDM4ESMN1; SMN2
	SCHEMBL26836954	0.77	MAPKAPK2 (0.56)	HTR2CPARP1MAPK10RIPK1MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.