SCHEMBL4101957

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13558137	0.93	KCNJ1 (0.38)	POLBKDM4EALDH1A1HTTL3MBTL1
	SCHEMBL9906207	0.84	KCNJ1 (0.39)	POLBKDM4EALDH1A1HTTMAPK1
	SCHEMBL4086916	0.82	KDM4E (0.38)	POLBKDM4EALDH1A1HTTMAPK1
	SCHEMBL4094175	0.82	KDM4E (0.38)	POLBKDM4EALDH1A1HTTMAPK1
	SCHEMBL9906212	0.82	KDM4E (0.38)	POLBKDM4EALDH1A1HTTMAPK1
	SCHEMBL9305546	0.81	ALDH1A1 (0.33)	POLBALDH1A1MAPK1NPC1LMNA
	SCHEMBL29299527	0.80	KCNJ1 (0.38)	POLBKDM4EALDH1A1HTTL3MBTL1
	SCHEMBL25271966	0.74	KCNJ1 (0.46)	POLBKDM4EALDH1A1HTTL3MBTL1
	SCHEMBL31539506	0.74	KCNJ1 (0.46)	POLBKDM4EALDH1A1HTTL3MBTL1
	SCHEMBL3420319	0.74	KCNJ1 (0.46)	POLBKDM4EALDH1A1HTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.