Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101957 | 0.81 | POLB (0.38) | ALDH1A1LMNAPOLBNPC1MAPK1 | |
| SCHEMBL9266166 | 0.81 | SLC6A9 (0.34) | SCN9ASLC6A9EGLN1POLB | |
| SCHEMBL1394889 | 0.80 | SLC6A9 (0.42) | ALDH1A1SLC6A9EGLN1POLBPDE4B | |
| SCHEMBL9205301 | 0.79 | EGLN1 (0.40) | ALDH1A1SLC6A9EGLN1POLBPDE4B | |
| SCHEMBL9024977 | 0.77 | SIGMAR1 (0.35) | SLC6A9POLB | |
| SCHEMBL7869921 | 0.76 | EGLN1 (0.39) | ALDH1A1SLC6A9EGLN1POLBPDE4B | |
| SCHEMBL25574097 | 0.76 | ALDH1A1 (0.45) | ALDH1A1SLC6A9EGLN1LMNATSHR | |
| SCHEMBL30764646 | 0.76 | NPC1 (0.35) | SLC6A9LMNAPOLBNPC1ALOX15 | |
| SCHEMBL7871400 | 0.75 | ALDH1A1 (0.40) | ALDH1A1EGLN1POLBNPC1ALOX15 | |
| SCHEMBL16800534 | 0.74 | NOS1 (0.43) | ALDH1A1SLC6A9EGLN1LMNAPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334371-A | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |