Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.64 |
| ▸ | PGR | P06401 | 14/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SHBG | P04278 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101587 | 0.89 | AR (0.65) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4106362 | 0.89 | AR (0.65) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4106194 | 0.89 | AR (0.65) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4101155 | 0.89 | AR (0.65) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4107839 | 0.86 | AR (0.66) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4113926 | 0.86 | AR (0.66) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4208646 | 0.85 | AR (0.63) | ARPGRNR3C2CYP3A4LMNA | |
| SCHEMBL4107420 | 0.84 | PGR (0.66) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4107733 | 0.82 | PGR (0.46) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4106247 | 0.82 | PGR (0.46) | ARPGRNR3C2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048218-A1 | 17Beta-CYANO-18A-HOMO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048218-A1 | 17Beta-CYANO-18A-HOMO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | HSD17B7, HSD17B11, CYP17A1 | AR 106/4885PGR 91/4885NR3C2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.