SCHEMBL4103121

SCHEMBL4103121

C/C=C(C(=C/C)/c1ccc(OC(C)=O)cc1)\c1ccc(OC(C)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.60
HSD17B10 Q99714 2/20 0.58
LMNA P02545 5/20 0.57
MAPT P10636 4/20 0.52
POLB P06746 2/20 0.52
PKM P14618 2/20 0.52
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
ESR1 P03372 2/20 0.51
ADORA3 P0DMS8 2/20 0.51
PGR P06401 1/20 0.51
CHRM2 P08172 1/20 0.51
AR P10275 1/20 0.51
CHRM1 P11229 1/20 0.51
SLC6A2 P23975 1/20 0.51
SLC6A3 Q01959 1/20 0.51
TP53 P04637 2/20 0.50
CYP3A4 P08684 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23457919 1.00 ELANE (0.60) ELANEHSD17B10LMNAMAPTPOLB
SCHEMBL651645 0.93 MAPT (0.61) ELANEHSD17B10LMNAMAPTPOLB
SCHEMBL9433106 0.87 ELANE (0.51) ELANEHSD17B10LMNAMAPTPOLB
Fenabutene SCHEMBL2111368 0.83 ELANE (0.60) ELANEHSD17B10LMNAMAPTPOLB
Fenabutene SCHEMBL28884548 0.83 ELANE (0.60) ELANEHSD17B10LMNAMAPTPOLB
Fenabutene SCHEMBL28884547 0.83 ELANE (0.60) ELANEHSD17B10LMNAMAPTPOLB
SCHEMBL9339013 0.82 ELANE (0.83) ELANEHSD17B10LMNAMAPTPOLB
SCHEMBL269329 0.82 LMNA (0.80) ELANEHSD17B10LMNAMAPTPOLB
SCHEMBL2697222 0.82 ELANE (0.63) ELANEHSD17B10LMNAMAPTPOLB
SCHEMBL5831549 0.80 ELANE (0.67) ELANEHSD17B10LMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1315454-C Topical compositions for regulating oily/shiny appearance of skin PROCTER & GAMBLE (US) 2007-05-16 CN claimed
WO-2021110987-A1 METHODS AND APPARATUSES FOR DIAGNOSING CANCER FROM CELL-FREE NUCLEIC ACIDS LIFE & SOFT (FR) 2021-06-10 WO disclosed
US-20090226558-A1 ORGANIC/NATURAL POULTRY FEED ADDITIVE C & R BIOTEK, LLC 2009-09-10 US disclosed
CN-1315454-C Topical compositions for regulating oily/shiny appearance of skin PROCTER & GAMBLE (US) 2007-05-16 CN disclosed
US-20050238597-A1 Topical treatment of acne, seborrheic dermatitis, and oily skin with formulations containing histamine antagonists DISCOVERY PARTNERS LLC 2005-10-27 US disclosed
EP-1035828-B1 TOPICAL COMPOSITIONS FOR REGULATING THE OILY/SHINY APPEARANCE OF SKIN PROCTER & GAMBLE (US) 2003-05-02 EP disclosed
EP-0719127-B1 DEPILATORY COMPOSITIONS COMPRISING SULFHYDRYL COMPOUNDS PROCTER & GAMBLE (US) 2001-09-19 EP disclosed
CN-1281354-A Topical composition for regulating oily/shiny appearance of skin PROCTER & GAMBLE (US) 2001-01-24 CN disclosed
US-6150403-A INHIBITING SEBACEOUS GLAND ACTIVITY IN MAMMALIAN SKIN AND SCALP BY TOPICALLY ADMINISTERING DEHYDROACETIC ACID OR SALT AND A DERMATOLOGICALLY ACCEPTABLE CARRIER; TREATING ACNE THE PROCTER & GAMBLE COMPANY (US) 2000-11-21 US disclosed
EP-1035828-A2 TOPICAL COMPOSITIONS FOR REGULATING THE OILY/SHINY APPEARANCE OF SKIN THE PROCTER & GAMBLE COMPANY (US) 2000-09-20 EP disclosed
US-5645825-A AND A CARRIER; TOPICAL APPLICATION TO FACE THE PROCTER & GAMBLE COMPANY (US) 1997-07-08 US disclosed
US-5587176-A SKIN DISORDERS THE PROCTER & GAMBLE COMPANY (US) 1996-12-24 US disclosed
CN-1131909-A Depilatory compositions comprising sulfhydral compounds PROCTER & GAMBLE (US) 1996-09-25 CN disclosed
EP-0719127-A1 DEPILATORY COMPOSITIONS COMPRISING SULFHYDRYL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1996-07-03 EP disclosed
CN-1123523-A Methods of using hesperetin for sebum control and treatment of ACNE PROCTER & GAMBLE (US) 1996-05-29 CN disclosed
EP-0695181-A1 METHODS OF USING HESPERETIN FOR SEBUM CONTROL AND TREATMENT OF ACNE THE PROCTER & GAMBLE COMPANY (US) 1996-02-07 EP disclosed
WO-1995033440-A1 DEPILATORY COMPOSITIONS COMPRISING SULFHYDRYL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1995-12-14 WO disclosed
WO-1995033439-A1 DEPILATORY COMPOSITIONS COMPRISING SULFHYDRYL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1995-12-14 WO disclosed
US-5362748-A Methods of using diethyldithiocarbamic acid for the prevention of hair growth THE PROCTER & GAMBLE COMPANY (US) 1994-11-08 US disclosed
WO-1994023717-A1 METHODS OF USING HESPERETIN FOR SEBUM CONTROL AND TREATMENT OF ACNE THE PROCTER & GAMBLE COMPANY (US) 1994-10-27 WO disclosed