Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ESR1 | P03372 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23457919 | 0.93 | ELANE (0.60) | MAPTLMNAMEN1KMT2AESR1 | |
| SCHEMBL4103121 | 0.93 | ELANE (0.60) | MAPTLMNAMEN1KMT2AESR1 | |
| SCHEMBL13057613 | 0.85 | ELANE (0.71) | MAPTLMNAMEN1KMT2AESR1 | |
| 4-Acetoxyphenol SCHEMBL203149 | 0.84 | LMNA (0.67) | MAPTLMNAMEN1KMT2AESR1 | |
| 4-Acetoxyphenol SCHEMBL27671868 | 0.82 | LMNA (0.64) | MAPTLMNAMEN1KMT2AESR1 | |
| 4-Acetoxyphenol SCHEMBL27952470 | 0.82 | LMNA (0.64) | MAPTLMNAMEN1KMT2AESR1 | |
| SCHEMBL9735377 | 0.81 | ELANE (0.56) | MAPTLMNAMEN1KMT2AESR1 | |
| SCHEMBL14360729 | 0.81 | ESR1 (0.60) | MAPTLMNAMEN1KMT2AESR1 | |
| SCHEMBL9433106 | 0.81 | ELANE (0.51) | MAPTLMNAMEN1KMT2AESR1 | |
| SCHEMBL6853303 | 0.79 | HSD17B10 (0.66) | MAPTLMNAMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022880-A2 | METHOD FOR SYNTHESIZING STEROIDS | UNIVERSITE DE STRASBOURG (FR) | 2012-02-23 | — | — | WO | claimed |
| US-7388003-B2 | Δ15-D-Homosteroids with androgenic action | BAYER SCHERING PHARMA AG (DE) | 2008-06-17 | — | — | US | claimed |
| US-20050131076-A1 | Delta15-D-Homosteroids with androgenic action | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | claimed |
| EP-0872467-B1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEM CO (US) | 2003-01-22 | — | — | EP | claimed |
| EP-1000065-A4 | PREPARATION OF OXYMORPHONE, OXYCODONE AND DERIVATIVES | PENICK CORP (US) | 2001-09-12 | — | — | EP | claimed |
| EP-1000065-A1 | PREPARATION OF OXYMORPHONE, OXYCODONE AND DERIVATIVES | Penick Corporation (US) | 2000-05-17 | — | — | EP | claimed |
| EP-0741730-B1 | 1-SUBSTITUTED-4-FLUORO-1,4-DIAZONIABICYCLO 2.2.2]OCTANE SALTS AND THEIR APPLICATION AS FLUORINATING AGENTS | ALLIED SIGNAL INC (US) | 1999-10-06 | — | — | EP | claimed |
| US-5922876-A | REACTING MORPHINE WITH ACYL HALIDE OR ANHYDRIDE TO FORM 3-ACYLMORPHINE, OXIDIZING HYDROXY GROUP OF ACYLMORPHINE WITH AN OXIDIZING AGENT, REACTING THE INTERMEDIATE WITH HYDROGEN PEROXIDE AND AN ACID, ACYLATING, HYDROGENATING AND HYDROLYSIS | PENICK CORPORATION (US) | 1999-07-13 | — | — | US | claimed |
| WO-1999002529-A1 | PREPARATION OF OXYMORPHONE, OXYCODONE AND DERIVATIVES | PENICK CORPORATION (US) | 1999-01-21 | — | — | WO | claimed |
| EP-0872467-A1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEMICAL COMPANY (US) | 1998-10-21 | — | — | EP | claimed |
| US-5606084-A | Process of fluorinating organic compounds with 1-substituted-4-fluoro-1,4-diazoniabicyclo octane salts | ALLIEDSIGNAL INC. (US) | 1997-02-25 | — | — | US | claimed |
| EP-0741730-A1 | 1-SUBSTITUTED-4-FLUORO-1,4-DIAZONIABICYCLO 2.2.2]OCTANE SALTS AND THEIR APPLICATION AS FLUORINATING AGENTS | AlliedSignal Inc. (US) | 1996-11-13 | — | — | EP | claimed |
| WO-1995017404-A1 | 1-SUBSTITUTED-4-FLUORO-1,4-DIAZONIABICYCLO[2.2.2]OCTANE SALTS AND THEIR APPLICATION AS FLUORINATING AGENTS | ALLIEDSIGNAL, INC. (US) | 1995-06-29 | — | — | WO | claimed |
| EP-0159823-B1 | PREPARATION OF 14-HYDROXY-N-ETHOXY-CARBONYL-NORCODEINONE | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1989-08-09 | — | — | EP | claimed |
| US-4639520-A | Preparation of 14-hydroxy-N-ethoxy-carbonyl-norcodeinone | MALLINCKRODT, INC. (US) | 1987-01-27 | — | — | US | claimed |
| EP-0159823-A1 | Preparation of 14-Hydroxy-N-Ethoxy-Carbonyl-Norcodeinone | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-10-30 | — | — | EP | claimed |
| EP-0158476-A1 | Preparation of noroxymorphone from morphine | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-10-16 | — | — | EP | claimed |
| JP-62029545-A | — | — | None | — | — | JP | disclosed |
| US-4055575-A | HYDROGENATION, SAPONIFICATION | SCM CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4039591-A | 1-ACETOXY-4-CHLORO-3-METHYLBUT-2-ENE | SCM CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131076-A1 | Delta15-D-Homosteroids with androgenic action | CYP17A1, HSD3B2, HSD3B1 | MAPT 3358/4885LMNA 2308/4885MEN1 666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.