Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 5/20 | 0.49 |
| ▸ | S100A4 | P26447 | 5/20 | 0.49 |
| ▸ | CDC25A | P30304 | 4/20 | 0.49 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583758 | 0.79 | HSP90AA1 (0.59) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL2901813 | 0.79 | FGFR1 (0.58) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL27460293 | 0.79 | HSP90AA1 (0.59) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL17969798 | 0.77 | HSP90AA1 (0.68) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL7098579 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAKDM4EHTT | |
| Anthraquinone SCHEMBL28258160 | 0.73 | MAPT (0.60) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL29941466 | 0.72 | CDC25B (0.68) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL571026 | 0.72 | CDC25B (0.68) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL13442857 | 0.72 | APEX1 (0.47) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL12761941 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247472-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | FLUOFARMA (FR) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247472-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | CCNA1, MKI67, CCNT1 | ALDH1A1 709/4885MAPT 3602/4885LMNA 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.