SCHEMBL17969798

SCHEMBL17969798

CCC(=O)C1=C(c2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 5/20 0.68
HSP90AB1 P08238 3/20 0.68
NPSR1 Q6W5P4 4/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
LMNA P02545 4/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
ALDH1A1 P00352 3/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
XBP1 P17861 2/20 0.61
HKDC1 Q2TB90 2/20 0.61
FGFR1 P11362 6/20 0.57
FGFR2 P21802 6/20 0.57
FGFR4 P22455 6/20 0.57
FGFR3 P22607 6/20 0.57
SRC P12931 3/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
MAPT P10636 5/20 0.53
HTT P42858 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19446018 0.82 HSP90AA1 (0.61) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL13679121 0.82 HSP90AA1 (0.61) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL17969802 0.81 HSP90AA1 (1.00) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL13770821 0.80 FGFR1 (0.85) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL21698051 0.80 HSP90AA1 (0.58) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL17969781 0.80 ALDH1A1 (0.78) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL17969803 0.78 HSP90AA1 (0.70) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL4103689 0.77 ALDH1A1 (0.50) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL17969780 0.77 FGFR1 (0.88) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA
SCHEMBL6651775 0.77 HSP90AA1 (0.68) HSP90AA1HSP90AB1NPSR1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 EP disclosed