Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 8/20 | 0.69 |
| ▸ | ABL1 | P00519 | 11/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099939 | 0.95 | KIT (0.67) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL4100085 | 0.91 | KIT (0.81) | KITABL1 | |
| SCHEMBL28054441 | 0.88 | ABL1 (0.69) | KITABL1 | |
| SCHEMBL4110676 | 0.88 | KIT (0.78) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL4070204 | 0.87 | KIT (0.75) | KITABL1 | |
| SCHEMBL4095171 | 0.85 | KIT (0.84) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL29493482 | 0.82 | KIT (1.00) | KITABL1CSF1R | |
| SCHEMBL30080656 | 0.82 | KIT (1.00) | KITABL1CSF1R | |
| SCHEMBL16236899 | 0.82 | KIT (0.86) | KIT | |
| SCHEMBL588975 | 0.82 | KIT (1.00) | KITABL1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176781-A1 | Acetylenic Heteroaryl Compounds | ARIAD PHARMACEUTICALS, INC. | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176781-A1 | Acetylenic Heteroaryl Compounds | NAT1, AADAC, ACACA | KIT 3086/4885ABL1 1035/4885FGFR1 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.