Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25265 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL26373 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL8504459 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL102590 | 0.73 | CYP2A6 (0.39) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL510351 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL510183 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL756551 | 0.68 | CYP2A6 (0.32) | — | |
| Acridine SCHEMBL8339 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL1772714 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL29352289 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10472381-B2 | Sialic acid derivatives | REINHARD BROSSMER (DE) | 2019-11-12 | — | — | US | disclosed |
| CN-109627215-A | A kind of fluorescent material, the preparation method of fluorescent material, display panel and display device | 京东方科技集团股份有限公司 | 2019-04-16 | — | — | CN | disclosed |
| WO-2018172129-A1 | SIALIC ACID DERIVATIVES WITH C-C TRIPLE BOND, AND PREPARATION THEREOF | PRESCHER HORST (CH) | 2018-09-27 | — | — | WO | disclosed |
| US-20160362436-A1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2016-12-15 | — | — | US | disclosed |
| EP-2797946-B1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-9260467-B2 | Sialic acid dimers | BROSSMER REINHARD (DE) | 2016-02-16 | — | — | US | disclosed |
| EP-2910561-A1 | Sialic acid derivatives | Brossmer, Reinhard (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-20150005245-A1 | Sialic Acid Dimers | BROSSMER REINHARD (DE) | 2015-01-01 | — | — | US | disclosed |
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-20090018264-A1 | RESIN COMPOSITION | CANON KABUSHIKI KAISHA (JP) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472381-B2 | Sialic acid derivatives | NEU1, NEU2, NEU3 | ALDH1A1 127/4885HPGD 717/4885GLA 62/4885 |
| US-20160362436-A1 | SIALIC ACID DERIVATIVES | NEU1, NEU2, NEU3 | ALDH1A1 127/4885HPGD 713/4885GLA 62/4885 |
| US-20150005245-A1 | Sialic Acid Dimers | SIGLEC9, SIGLEC7, NEU2 | ALDH1A1 284/4885HPGD 918/4885GLA 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.