⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7715458 | 0.96 | LMNA (0.43) | — | |
| Hydrochloric Acid SCHEMBL9247398 | 0.96 | LMNA (0.43) | — | |
| Acetic Acid SCHEMBL7719636 | 0.89 | FFAR3 (0.50) | — | |
| SCHEMBL9670217 | 0.89 | LMNA (0.38) | — | |
| SCHEMBL131091 | 0.86 | — | — | |
| Acetic Acid SCHEMBL27557856 | 0.86 | FFAR3 (0.47) | — | |
| SCHEMBL925909 | 0.86 | — | — | |
| SCHEMBL13542982 | 0.83 | LMNA (0.33) | — | |
| SCHEMBL7344745 | 0.83 | — | — | |
| SCHEMBL17222510 | 0.83 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118342877-A | Self-adaptive anti-icing composite material and preparation method and application thereof | 西安理工大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118039842-A | Surface treatment method for lithium battery positive electrode material and lithium battery positive electrode material | 陕西彩虹新材料有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-112174788-B | Preparation method of 2, 6-tetraethyl-3, 5-heptane dione | 浙江凯普化工有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-111359258-B | Novel system for separating and purifying hydrophobic eutectic solvent of weak protonic acid and method for purifying weak protonic acid | 哈尔滨工业大学（威海） | 2021-11-23 | — | — | CN | claimed |
| CN-112174788-A | Preparation method of 2,2,6,6-tetraethyl-3, 5-heptanedione | 浙江凯普化工有限公司 | 2021-01-05 | — | — | CN | claimed |
| EP-2847168-A1 | ANTIBACTERIAL AGENTS | Achaogen, Inc. (US) | 2015-03-18 | — | — | EP | claimed |
| WO-2013170165-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2013-11-14 | — | — | WO | claimed |
| EP-1789377-B1 | ALTERNATIVE SYNTHESIS OF RENIN INHIBITORS AND INTERMEDIATES THEREOF | NOVARTIS AG (CH) | 2010-10-20 | — | — | EP | claimed |
| WO-2010076717-A1 | ION-SELECTIVE SOLID CONTACT MICROELECTRODE AND ITS PRODUCTION METHOD | UNIVERSIDADE DE AVEIRO (PT) | 2010-07-08 | — | — | WO | claimed |
| US-7709532-B2 | Methods for improving bioavailability of a renin inhibitor | NOVARTIS AG (CH) | 2010-05-04 | — | — | US | claimed |
| WO-2005058291-A1 | MICROEMULSION PRECONCENTRATE COMPRISING A RENIN INHIBITOR | NOVARTIS AG (CH) | 2005-06-30 | — | — | WO | claimed |
| US-20040266836-A1 | Salt of acidic AT1-receptor antagonist and basic cardiovascular ingredient; potentiation or synergism; reduction of side effects | BUHLMAYER PETER (CH) | 2004-12-30 | — | — | US | claimed |
| EP-1448190-A2 | SALTS FORMED OF AN AT1-RECEPTOR ANTAGONIST AND A CARDIOVASCULAR AGENT | Novartis AG (CH) | 2004-08-25 | — | — | EP | claimed |
| WO-2003035046-A2 | SALTS FORMED OF AN AT1-RECEPTOR ANTAGONIST AND A CARDIOVASCULAR AGENT | NOVARTIS AG (CH) | 2003-05-01 | — | — | WO | claimed |
| CN-1332734-A | Novel malonic acid derivatives, processes for their preparation, their use and pharmaceutical compositions containing them (inhibition of factor xa activity | AVENTIS PHARMA GMBH (DE) | 2002-01-23 | — | — | CN | claimed |
| EP-1140878-A1 | NOVEL MALONIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ( INHIBITIO OF FACTOR XA ACTIVITY ) | Aventis Pharma Deutschland GmbH (DE) | 2001-10-10 | — | — | EP | claimed |
| WO-2000040571-A1 | NOVEL MALONIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM (INHIBITION OF FACTOR XA ACTIVITY) | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-07-13 | — | — | WO | claimed |
| EP-0481214-B1 | Prodrugs of phosphonates | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1998-06-24 | — | — | EP | claimed |
| US-5276152-A | Process for the production of 4,6-dialkoxypyrimidines | LONZA LTD. (CH) | 1994-01-04 | — | — | US | claimed |
| EP-0552759-A1 | Process for preparation of 4,6-dialkoxypyrimidines | LONZA AG (CH) | 1993-07-28 | — | — | EP | claimed |