⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410733 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL7715458 | 0.79 | LMNA (0.43) | — | |
| Hydrochloric Acid SCHEMBL9247398 | 0.79 | LMNA (0.43) | — | |
| SCHEMBL9670217 | 0.73 | LMNA (0.38) | — | |
| Acetic Acid SCHEMBL7719636 | 0.73 | FFAR3 (0.50) | — | |
| SCHEMBL845168 | 0.72 | — | — | |
| SCHEMBL131091 | 0.71 | — | — | |
| SCHEMBL925909 | 0.71 | — | — | |
| Acetic Acid SCHEMBL27557856 | 0.71 | FFAR3 (0.47) | — | |
| SCHEMBL1263346 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |
| US-5627182-A | RENIN INHIBITORS FOR USE AS HYPOTENSIVE AGENTS | CIBA GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | claimed |