Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | CDK9 | P50750 | 4/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244349 | 0.91 | CDK9 (0.60) | ADORA3CDK9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4098044 | 0.87 | EGFR (0.54) | ADORA3CDK9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1243636 | 0.84 | CDK9 (0.46) | ADORA3CDK9CYP1A2CYP2C19HDAC1 | |
| SCHEMBL5734993 | 0.81 | EGFR (0.68) | ADORA3CDK9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4108197 | 0.80 | EGFR (0.53) | ADORA3CDK9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1243609 | 0.80 | CDK9 (0.65) | CDK9CYP1A2CYP2D6CYP2C19CLK4 | |
| SCHEMBL4108457 | 0.79 | CYP1A2 (0.58) | CDK9CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4108453 | 0.77 | ABL1 (0.57) | ADORA3CDK9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4790476 | 0.74 | EGFR (0.67) | ADORA3CDK9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4116500 | 0.74 | CDK9 (0.55) | ADORA3CDK9CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221581-A1 | Methods of treating pain | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221581-A1 | Methods of treating pain | CDK5, CAMKK2, CDK3 | ADORA3 1865/4885CDK9 97/4885PTK2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.