SCHEMBL4108586

SCHEMBL4108586

C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)CCN1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PTGDR2 Q9Y5Y4 17/20 0.67
▸ CCR1 P32246 3/20 0.50
▸ FPR3 P25089 1/20 0.50
▸ GPR65 Q8IYL9 1/20 0.50
▸ GPR35 Q9HC97 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1714001 0.93 PTGDR2 (0.65) PTGDR2CCR1FPR3GPR65GPR35
SCHEMBL1713555 0.89 PTGDR2 (0.56) PTGDR2
SCHEMBL4108820 0.88 PTGDR2 (0.80) PTGDR2
SCHEMBL1714986 0.87 PTGDR2 (0.57) PTGDR2
SCHEMBL4114701 0.87 PTGDR2 (0.63) PTGDR2CCR1FPR3GPR65GPR35
SCHEMBL27340749 0.83 PTGDR2 (0.61) PTGDR2CCR1FPR3GPR65GPR35
SCHEMBL30902461 0.83 PTGDR2 (0.61) PTGDR2CCR1FPR3GPR65GPR35
SCHEMBL27340739 0.83 PTGDR2 (0.61) PTGDR2CCR1FPR3GPR65GPR35
SCHEMBL1714266 0.81 PTGDR2 (0.55) PTGDR2CCR1
SCHEMBL30902439 0.81 PTGDR2 (0.62) PTGDR2CCR1FPR3GPR65GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524715-B2 Phenoxyacetic acid derivatives useful for treating respiratory diseases ASTRAZENECA AB (SE) 2013-09-03 — — US disclosed
US-20090149448-A1 Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases ASTRAZENECA AB (SE) 2009-06-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149448-A1 Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases PAOX, PCCA, PAH PTGDR2 236/4885CCR1 1747/4885FPR3 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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