Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4108586 | 0.87 | PTGDR2 (0.67) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL27340004 | 0.83 | PTGDR2 (0.58) | PTGDR2ENPP2MGLLSCN9A | |
| SCHEMBL30902364 | 0.83 | PTGDR2 (0.58) | PTGDR2ENPP2MGLLSCN9A | |
| SCHEMBL1714001 | 0.80 | PTGDR2 (0.65) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL13813451 | 0.79 | PTGDR2 (0.87) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL1714600 | 0.79 | PTGDR2 (0.87) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL1713946 | 0.77 | PTGDR2 (1.00) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL13800164 | 0.77 | PTGDR2 (0.49) | PTGDR2MGLLSCN9A | |
| SCHEMBL1714483 | 0.77 | PTGDR2 (0.86) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL1713555 | 0.76 | PTGDR2 (0.56) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | PAOX, PCCA, PAH | PTGDR2 236/4885ENPP2 162/4885MGLL 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.