Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930244 | 0.91 | CHEK1 (0.41) | ALDH1A1GAANPC1NR1H4PPARA | |
| SCHEMBL979627 | 0.85 | ALDH1A1 (0.63) | ALDH1A1GAANPC1NR1H4PPARA | |
| SCHEMBL976561 | 0.81 | PTGES (0.53) | FFAR1 | |
| SCHEMBL977932 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GAANPC1NR1H4PPARA | |
| SCHEMBL979194 | 0.79 | KMT2A (0.62) | ALDH1A1GAANPC1MEN1KMT2A | |
| SCHEMBL979104 | 0.78 | PTGES2 (0.43) | ALDH1A1GAANPC1MEN1KMT2A | |
| SCHEMBL978370 | 0.77 | HDAC6 (0.48) | GAAMAPT | |
| SCHEMBL978358 | 0.74 | PTGES2 (0.59) | ALDH1A1NPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL979379 | 0.74 | GAA (0.61) | ALDH1A1GAANPC1PPARAMEN1 | |
| SCHEMBL977985 | 0.74 | HDAC6 (0.57) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064250-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |