Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124959 | 0.71 | HSD11B1 (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL4110065 | 0.70 | HSD11B1 (0.55) | HSD11B1HSD11B2 | |
| SCHEMBL9395018 | 0.70 | HSD11B1 (0.64) | HSD11B1HSD11B2 | |
| SCHEMBL3709006 | 0.69 | HSD11B1 (0.44) | HSD11B1HSD11B2 | |
| SCHEMBL4118605 | 0.69 | HSD11B1 (0.47) | HSD11B1HSD11B2 | |
| SCHEMBL4112653 | 0.68 | HSD11B1 (0.72) | HSD11B1HSD11B2 | |
| SCHEMBL1223445 | 0.68 | HSD11B1 (0.53) | HSD11B1HSD11B2 | |
| SCHEMBL1222094 | 0.67 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| SCHEMBL4113451 | 0.67 | HSD11B1 (0.71) | HSD11B1HSD11B2 | |
| SCHEMBL1222267 | 0.67 | HSD11B1 (0.71) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064187-A2 | INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | Vitae Pharmaceuticals, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008024497-A2 | INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE TYPE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2008-02-28 | — | — | WO | disclosed |