SCHEMBL4112

SCHEMBL4112

CN(C(=O)COc1ccccc1)c1ccccc1C(=O)NCc1ccco1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 9/20 0.57
HSD17B10 Q99714 5/20 0.57
MAPT P10636 3/20 0.57
TSHR P16473 2/20 0.57
TP53 P04637 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
POLB P06746 5/20 0.53
ALDH1A1 P00352 4/20 0.53
SGMS2 Q8NHU3 1/20 0.53
KDM4E B2RXH2 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HTT P42858 1/20 0.51
LMNA P02545 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
DNMT1 P26358 1/20 0.49
ALOX12 P18054 1/20 0.48
ESR1 P03372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guaifenesin SCHEMBL28086731 0.86 TSHR (0.48) HPGDHSD17B10MAPTTSHRTP53
SCHEMBL12861415 0.75 ALDH1A1 (0.73) HPGDHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL23412369 0.73 HPGD (0.62) HPGDHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL30093022 0.73 HPGD (0.62) HPGDHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL31541280 0.73 SMN1; SMN2 (0.51) HPGDHSD17B10MAPTTSHRTP53
SCHEMBL12172824 0.72 NPSR1 (0.72) HPGDHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL31238983 0.70 HPGD (0.67) HPGDHSD17B10MAPTTSHRTP53
SCHEMBL31239049 0.69 SMN1; SMN2 (0.81) HPGDHSD17B10MAPTTSHRTP53
SCHEMBL16676602 0.69 HPGD (0.66) HPGDHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL29061003 0.69 HPGD (0.52) HPGDHSD17B10MAPTTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22887 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3836899-B1 CHEMOTHERAPEUTIC PHARMACEUTICAL SUSPENSION FOR ORAL DOSAGE ONCOSOL LTD (GB) 2026-05-27 EP claimed
CN-122075406-A Ensifen pharmaceutical composition, preparation method and application thereof 2026-05-26 CN claimed
WO-2026102187-A1 ENGINEERED VIRUS-LIKE PARTICLES COMPRISING A BASE EDITOR FOR THE TREATMENT OF GLAUCOMA, AND APPLICATIONS THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-15 WO claimed
EP-4735467-A1 SARS-COV-2 PROTEIN EPITOPES AND USE THEREOF IN PREVENTION AND DIAGNOSIS OF CORONAVIRUS INFECTIONS Instytut Immunologii I Terapii Doswiadczalnej Im.Ludwika Hirszfelda Pan We Wroclawiu (PL) 2026-05-06 EP claimed
WO-2026090131-A1 METHODS OF DESICCATING A SAMPLE AND USE THEREOF AMERICAN TYPE CULTURE COLLECTION (US) 2026-04-30 WO claimed
US-20260115155-A1 STABLE FORMS OF CAPSAICIN PALMITATE FOR THE TREATMENT OF PAIN CHORDA PHARMA INC (US) 2026-04-30 US claimed
EP-4725551-A1 FUSION POLYPEPTIDE AJ007 AND USE THEREOF Nanjing Anji Biotechnology Co., Ltd. (CN) 2026-04-15 EP claimed
US-12599556-B2 Ophthalmic compositions BIOTHERAVISION INC. (US) 2026-04-14 US claimed
US-12599572-B2 Solid lipid nanoparticles of curcumin Punjab University Chandigarh (IN) 2026-04-14 US claimed
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 EP claimed
WO-1993018852-A9 OIL-IN-WATER EMULSIONS OF POSITIVELY CHARGED PARTICLES 1994-01-06 WO claimed
EP-0577215-A1 Surface modified anticancer nanoparticles NanoSystems L.L.C. (US) 1994-01-05 EP claimed
EP-0564510-A1 METHOD AND COMPOSITION FOR DISINFECTING CONTACT LENSES ALLERGAN, INC (US) 1993-10-13 EP claimed
WO-1993018852-A1 OIL-IN-WATER EMULSIONS OF POSITIVELY CHARGED PARTICLES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1993-09-30 WO claimed
WO-1992011876-A1 METHOD AND COMPOSITION FOR DISINFECTING CONTACT LENSES SCHERING CORPORATION (US) 1992-07-23 WO claimed
US-5110806-A Dipalmitoyl phosphatidyl choline, fatty alcohol, tyloxapol THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-05-05 US claimed
US-4826821-A DIPALITOYLPHOSPHATIDYL CHLOINE, FATTY ALCOHOL, NONIONIC ETHER SURFACTANT, SODIUM CHLORIDE, RESPIROATORY DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1989-05-02 US claimed
US-4734222-A Composition and method for cleaning soft and hard contact lenses CIBA-GEIGY CORPORATION (US) 1988-03-29 US claimed
EP-0240464-A1 Cleaning compositions for soft and hard contact lens CIBA-GEIGY AG (CH) 1987-10-07 EP claimed
US-4127423-A SODIUM SILICATE, SODIUM CHLORIDE, ETHYLENEDIAMINETETRAACETIC ACID, A CELLULOSE POLYVINYL ALCOHOL, NONIONIC SURFACTANT BURTON, PARSONS AND COMPANY, INC. (US) 1978-11-28 US claimed