⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13222310 | 1.00 | — | — | |
| SCHEMBL410593 | 1.00 | — | — | |
| SCHEMBL12295947 | 1.00 | — | — | |
| SCHEMBL13243224 | 0.82 | — | — | |
| SCHEMBL14851701 | 0.81 | KDM4E (0.33) | — | |
| SCHEMBL20063376 | 0.81 | OPRM1 (0.38) | — | |
| SCHEMBL20063356 | 0.81 | OPRM1 (0.38) | — | |
| SCHEMBL13407354 | 0.77 | — | — | |
| SCHEMBL12328266 | 0.77 | — | — | |
| SCHEMBL22062983 | 0.77 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090483-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2013-04-11 | — | — | US | disclosed |
| US-8344162-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2013-01-01 | — | — | US | disclosed |
| US-20120271057-A9 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2012-10-25 | — | — | US | disclosed |
| US-20120065408-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2012-03-15 | — | — | US | disclosed |
| US-8080673-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2011-12-20 | — | — | US | disclosed |
| US-20100217014-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2010-08-26 | — | — | US | disclosed |