Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4117102 | 0.93 | ALDH1A1 (0.61) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4110198 | 0.85 | MAPT (0.54) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4112569 | 0.84 | ALDH1A1 (0.63) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4106770 | 0.82 | ALDH1A1 (0.65) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4104151 | 0.81 | ALDH1A1 (0.62) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL14955157 | 0.81 | MAPT (0.79) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4124060 | 0.81 | ALDH1A1 (0.61) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4125697 | 0.81 | ALDH1A1 (0.61) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4112553 | 0.80 | ALDH1A1 (0.49) | MAPTNPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL4112118 | 0.80 | ALDH1A1 (0.60) | MAPTNPSR1ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029983-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTI-HBV ACTIVITY | VALEANT RESEARCH & DEVELOPMENT (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029983-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTI-HBV ACTIVITY | HCCS, HAVCR2, HMBS | MAPT 4567/4885NPSR1 4354/4885ALDH1A1 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.