Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072284 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL28678725 | 0.75 | CA1 (0.37) | — | |
| SCHEMBL21253999 | 0.72 | — | — | |
| SCHEMBL9054539 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL5456824 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL12248215 | 0.69 | — | — | |
| SCHEMBL7089937 | 0.69 | — | — | |
| SCHEMBL12213320 | 0.69 | — | — | |
| SCHEMBL10596836 | 0.69 | KDM4E (0.35) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL18697531 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090226392-A1 | Phosphate-Binding Polymers for Oral Administration | GELTEX, INC. | 2009-09-10 | — | — | US | disclosed |
| US-7459151-B2 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2008-12-02 | — | — | US | disclosed |
| US-20060171916-A1 | Phosphate-binding polymers for oral administration | HOLMES-FARLEY STEPHEN R | 2006-08-03 | — | — | US | disclosed |
| US-7014846-B2 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2006-03-21 | — | — | US | disclosed |
| US-6858203-B2 | Method of making phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040191212-A1 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2004-09-30 | — | — | US | disclosed |
| US-20030133902-A1 | Method of making phosphate-binding polymers for oral administration | GELTEX PHARMACEUTICALS, INC. | 2003-07-17 | — | — | US | disclosed |
| US-6509013-B1 | Water insoluble crosslinked allyl amine homo- or copolymer and carrier; removing phosphate from gastrointestinal tract; hyperphosphatemia | GELTEX PHARMACEUTICALS, INC. | 2003-01-21 | — | — | US | disclosed |
| US-5667775-A | TREATMENT OF HYPERPHOSPHATEMIA, ION EXCHANGING, CATIONIC POLYMERS, REMOVAL OF PHOSPHATE FROM GASTROINTESTINAL TRACT | GELTEX PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226392-A1 | Phosphate-Binding Polymers for Oral Administration | PHPT1, SLC34A2, ALPI | KDM4E 4134/4885MAPT 1886/4885THRB 1295/4885 |
| US-20030133902-A1 | Method of making phosphate-binding polymers for oral administration | SI, PHPT1, ALPI | KDM4E 4252/4885MAPT 2148/4885THRB 2117/4885 |
| US-20040191212-A1 | Phosphate-binding polymers for oral administration | PHPT1, SLC34A2, ALPI | KDM4E 4134/4885MAPT 1886/4885THRB 1295/4885 |
| US-20060171916-A1 | Phosphate-binding polymers for oral administration | PHPT1, SLC34A2, ALPI | KDM4E 4134/4885MAPT 1886/4885THRB 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.