SCHEMBL411361

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL410998	0.93	CHEK1 (0.37)	CHEK1NPC1RAB9ATUBB4ATUBB
	SCHEMBL411959	0.90	CHEK1 (0.40)	CHEK1MAPTLMNAALDH1A1TUBB4A
	SCHEMBL412515	0.83	GAA (0.43)	MAPTNPC1RAB9AMAPK1MEN1
	SCHEMBL411561	0.83	CYP2D6 (0.45)	MAPTNPC1MEN1LMNAGAA
	SCHEMBL413452	0.83	SMPD3 (0.41)	CHEK1ALOX5MAPTNPC1RAB9A
	SCHEMBL411571	0.83	KMT2A (0.44)	CHEK1MAPTNPC1RAB9AGFER
	SCHEMBL412737	0.82	TUBB4A (0.51)	MAPTNPC1RAB9AMEN1LMNA
	SCHEMBL413607	0.82	TUBB4A (0.39)	GABRA1GABRB2ALOX5MAPTNPC1
	SCHEMBL14847368	0.82	CHEK1 (0.49)	CHEK1LMNAGAAALDH1A1
	SCHEMBL407088	0.82	CHEK1 (0.49)	CHEK1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.