SCHEMBL411454

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13041260	0.88	NPSR1 (0.50)	POLBNPSR1LMNANPC1LTB4R
	SCHEMBL412790	0.87	NPSR1 (0.41)	POLBNPSR1LMNANPC1LTB4R
	Hydrochloric Acid SCHEMBL4629522	0.87	NPSR1 (0.41)	POLBNPSR1LMNANPC1LTB4R
	SCHEMBL3300296	0.87	NPSR1 (0.43)	POLBNPSR1LMNARXFP1NPC1
	Hydrochloric Acid SCHEMBL411516	0.86	NPSR1 (0.42)	POLBNPSR1LMNARXFP1NPC1
	SCHEMBL411323	0.86	RXFP1 (0.38)	LMNARXFP1MAOBMAPTKMT2A
	SCHEMBL413515	0.85	EGFR (0.43)	POLBNPSR1LTB4RKMT2A
	SCHEMBL3303665	0.85	NPC1 (0.39)	POLBNPSR1RXFP1NPC1MAPT
	SCHEMBL3304869	0.84	RXFP1 (0.40)	LMNARXFP1LTB4RMAPTKMT2A
	SCHEMBL14401731	0.84	NPSR1 (0.39)	POLBNPSR1LMNANPC1LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.