Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | CD4 | P01730 | 2/20 | 0.71 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680049 | 0.94 | CD4 (0.70) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL13925192 | 0.90 | CD4 (0.81) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL13925209 | 0.89 | CD4 (0.80) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL4103044 | 0.88 | CD4 (0.69) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL4114411 | 0.88 | CD4 (0.69) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL13925220 | 0.85 | CD4 (0.74) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL1258731 | 0.85 | CD4 (0.74) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL13925221 | 0.84 | CD4 (0.73) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL13925218 | 0.84 | CD4 (0.80) | NPSR1CD4SORT1TSHRALDH1A1 | |
| SCHEMBL4113774 | 0.84 | CD4 (0.80) | NPSR1CD4SORT1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019423-A1 | Anti-viral triaza compounds | BELL THOMAS W (US) | 2002-02-14 | — | — | US | claimed |
| US-6342492-B1 | VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-01-29 | — | — | US | claimed |
| EP-0809504-A4 | ANTI-VIRAL TRIAZA COMPOUNDS | UNIV NEW YORK STATE RES FOUND (US) | 1998-11-04 | — | — | EP | claimed |
| EP-0809504-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-12-03 | — | — | EP | claimed |
| WO-1996025167-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-08-22 | — | — | WO | claimed |
| US-20090048222-A1 | Triaza Compound Immunoregulatory Agents | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO | 2009-02-19 | — | — | US | disclosed |
| US-20090048222-A1 | Triaza Compound Immunoregulatory Agents | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO | 2009-02-19 | — | — | US | disclosed |
| US-20090048222-A1 | Triaza Compound Immunoregulatory Agents | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO | 2009-02-19 | — | — | US | disclosed |
| US-20040220164-A1 | Triaza compound immunoregulatory agents | BELL THOMAS (US) | 2004-11-04 | — | — | US | disclosed |
| WO-2002080856-A2 | TRIAZA COMPOUND IMMUNOREGULATORY AGENTS | UNIVERSITY AND COMMUNITY COLLEGE SYSTEM OF NEVADA ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2002-10-17 | — | — | WO | disclosed |
| US-20020019423-A1 | Anti-viral triaza compounds | BELL THOMAS W (US) | 2002-02-14 | — | — | US | disclosed |
| US-6342492-B1 | VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-01-29 | — | — | US | disclosed |
| EP-0809504-A4 | ANTI-VIRAL TRIAZA COMPOUNDS | UNIV NEW YORK STATE RES FOUND (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0809504-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-12-03 | — | — | EP | disclosed |
| US-5663161-A | TRIAZACYCLO COMPOUNDS AS VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1996025167-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019423-A1 | Anti-viral triaza compounds | ZC3HAV1, MAVS, BAZ1A | NPSR1 4250/4885CD4 10/4885SORT1 4881/4885 |
| US-20040220164-A1 | Triaza compound immunoregulatory agents | CD4, NFATC1, IKZF3 | NPSR1 1972/4885CD4 1/4885SORT1 4792/4885 |
| US-20090048222-A1 | Triaza Compound Immunoregulatory Agents | CD4, NFATC1, IKZF3 | NPSR1 1972/4885CD4 1/4885SORT1 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.