SCHEMBL411500

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10189557	0.86	ALDH1A1 (0.47)	SMN1; SMN2ALDH1A1FYNMEN1KMT2A
	SCHEMBL411117	0.83	ALDH1A1 (0.67)	SMN1; SMN2ALDH1A1FYNPTGS1PTGS2
	SCHEMBL406868	0.83	PTGS1 (0.57)	SMN1; SMN2ALDH1A1PTGS1PTGS2
	SCHEMBL13040943	0.83	FLT3 (0.54)	SMN1; SMN2ALDH1A1TUBB4ATUBBTUBA3C
	SCHEMBL411799	0.82	ALDH1A1 (0.52)	SMN1; SMN2ALDH1A1PTGS1PTGS2
	SCHEMBL408616	0.82	ALDH1A1 (0.52)	SMN1; SMN2ALDH1A1TUBB4ATUBBTUBA3C
	SCHEMBL411865	0.82	PTGS1 (0.56)	SMN1; SMN2ALDH1A1FYNPTGS1PTGS2
	SCHEMBL413952	0.82	ALDH1A1 (0.49)	SMN1; SMN2ALDH1A1TUBB4ATUBBTUBA3C
	SCHEMBL407546	0.82	ALDH1A1 (0.52)	SMN1; SMN2ALDH1A1FYNPTGS1PTGS2
	SCHEMBL411830	0.81	ALDH1A1 (0.42)	SMN1; SMN2ALDH1A1FYNMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.